Human genome

No molecule in the history of science has reached the iconic status of the double helix of DNA. Its image has been imprinted on all aspects of society, from science, art, music, cinema, architecture and advertising. This review of the Mona Lisa of science examines the evolution of its form at the hands of both science and art.

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Advances in technology have enabled researchers to sequence the large regions of repetitive DNA that eluded the Human Genome Project.

Human DNA sequence. Computer screen display of a human DNA (deoxyribonucleic acid) sequence as a series of coloured bands.

Human Genome Project - Genome Mapping, DNA Sequencing, Genomics: The International HapMap Project, genomics studies, the Entrez Genome database, and the BLAST software tool allow the study of genetic similarity and divergence among humans and between species. The influence of the genome on health has led to personalized medicine. CODIS and comparative DNA sequence analyses have revolutionized the fields of forensics and anthropology, respectively.

2000- The Human Genome Project announced in June 2000 that they had created a ‘working draft’ of the entire human genome, the entire genetic code for one human being!

Why does a virus leave one child paralyzed and others unscathed? Priya Duggal looks for clues in the human genome.

Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applications.

An insight borrowed from computer science suggests that evolution values both fitness and diversity

Researchers added 200 million DNA base pairs and 115 protein-coding genes — but they’ve yet to entirely sequence the Y chromosome.