Clostridium perfringens enterotoxin (CPE) is responsible for causing the gastrointestinal
symptoms of several C. perfringens food- and nonfood-borne human gastrointestinal diseases. …

Clostridium perfringens uses its arsenal of >16 toxins to cause histotoxic and intestinal
infections in humans and animals. It has been unclear why this bacterium produces so many …

Clostridium perfringens relies upon plasmid-encoded toxin genes to cause intestinal
infections. These toxin genes are associated with insertion sequences that may facilitate their …

Several enteric clostridial diseases can affect humans and animals. Of these, the enteric
infections caused by Clostridium perfringens and Clostridium difficile are amongst the most …

Objective— Adequate platelet reactivity is required for maintaining hemostasis. However,
excessive platelet reactivity can also lead to the formation of occlusive thrombi. Platelet 12(S)-…

The Borrelia burgdorferi Rrp1 protein is a diguanylate cyclase that controls a regulon consisting
of ∼10% of the total genome. Because Rrp1 lacks a DNA-binding domain, its regulatory …

Autosomal recessive congenital ichthyosis (ARCI) is a diverse group of cornification diseases
associated with severe clinical complications and decreased quality of life. Germline …

Epsilon toxin (ETX), produced by Clostridium perfringens types B and D, is responsible for
diseases that occur mostly in ruminants. ETX is produced in the form of an inactive prototoxin …

The ability of Clostridium perfringens type C to cause human enteritis necroticans (EN) is
attributed to beta toxin (CPB). However, many EN strains also express C. perfringens …

Clostridium perfringens enterotoxin causes the gastrointestinal (GI) symptoms of C. perfringens
type A food poisoning and CPE-associated non-food-borne human GI diseases. It is well …