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- CreatorDavid ShoreStarsHugh LaurieOmar EppsRobert Sean LeonardUsing a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- CreatorAlan BallStarsAnna PaquinStephen MoyerSam TrammellTelepathic waitress Sookie Stackhouse encounters a strange new supernatural world when she meets the mysterious Bill Compton, a southern Louisiana gentleman and vampire.
- CreatorChris CarterStarsDavid DuchovnyGillian AndersonMitch PileggiTwo F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- CreatorKevin WilliamsonStarsKevin BaconJames PurefoyShawn AshmoreA brilliant, charismatic, and psychotic serial killer communicates with other active serial killers and activates a cult of believers who follow his every command.
- CreatorKelly MarcelCraig SilversteinStarsJason O'MaraShelley ConnChristine AdamsCenters on the Shannons, an ordinary family from 2149 when the planet is dying, who are transported back 85 million years to prehistoric Earth where they join Terra Nova, a colony of humans with a second chance to build a civilization.
- CreatorLouis C.K.StarsLouis C.K.Hadley DelanyUrsula ParkerThe life of Louie C.K., a divorced comedian living in New York with two kids.
- CreatorJosh FriedmanStarsLena HeadeyThomas DekkerSummer GlauSet after the events in Terminator 2: Judgment Day (1991), Sarah Connor and her son, John, try to stay under-the-radar from the government, as they plot to destroy the computer network, Skynet, in hopes of preventing Armageddon.
- CreatorJ.H. WymanStarsKarl UrbanMichael EalyMinka KellyIn a not-so-distant future, a human cop and an android partner team up to serve and protect.
- CreatorSam RaimiJohn SchulianR.J. StewartStarsLucy LawlessRenée O'ConnorTed RaimiXena, a mighty Warrior Princess with a dark past, sets out to redeem herself. She is joined by small town bard, Gabrielle. Together they journey the ancient world and fight for the greater good against ruthless Warlords and Gods.
- CreatorSteven LilienElizabeth SarnoffBryan WynbrandtStarsSarah JonesJorge GarciaJonny CoyneIn 1963, all the prisoners and guards mysteriously disappear from Alcatraz. In the present day, they resurface and a secret agency are tasked with re-capturing them.
- CreatorMatthew MillerStarsDamon WayansKeesha SharpKevin RahmA slightly unhinged ex-Navy SEAL Martin Riggs moves to California and starts working at the LAPD. He is paired with a veteran Detective Roger Murtaugh and together, they fight some of the most dangerous criminals in the city.
- CreatorDarren StarStarsJason PriestleyShannen DohertyLuke PerryA group of friends living in Beverly Hills, California make their way through life from their school days into adulthood.
- CreatorJames CameronCharles H. EgleeStarsJessica AlbaMichael WeatherlyRichard GunnA group of genetically-enhanced children escape from a lab project. Years later we meet Max, one of the escapees who now works for a messenger service in the post-apocalyptic Pacific Northwest.
- CreatorChristian WilliamsStarsKevin SorboMichael HurstKevin SmithHercules is half-man, half-god and a hero of fantastic strength. After his malevolent stepmother, Hera, kills his wife and children, he wanders about Earth with mortal best friend Iolaus, fighting evil and trying to overcome his loss.
- CreatorVictor FrescoStarsJay HarringtonPortia de RossiAndrea AndersIn an amoral science-based company, a manager tries to keep control of his scientists while being pressured by his shrewd boss.
- CreatorTracy TorméRobert K. WeissStarsJerry O'ConnellSabrina LloydJohn Rhys-DaviesA boy genius and his comrades travel to different parallel universes, trying to find their way back home.
- CreatorJonathan E. SteinbergStarsMark ValleyChi McBrideJackie Earle HaleyA unique bodyguard protects his clients by secretly infiltrating their lives in order to draw out and eliminate threats.
- CreatorJudd ApatowStarsJay BaruchelCarla GalloCharlie HunnamCollege freshman Steve Karp, his girlfriend and their fellow dormmates embark on one of the greatest experiences of their lives. Unfortunately for Steve, his lonely and recently divorced father is tagging along for the ride.
- CreatorJon Harmon FeldmanStarsEliza DushkuShawn ReavesZach GalifianakisA university graduate working in the city morgue is able to repeat the same day over again to prevent murders or other disasters.
- CreatorHart HansonStarsGeoff StultsMaddie HassonMercedes MasonAn Iraq war vet suffers a brain injury that triggers the ability to see connections between seemingly unrelated events, objects or people.
- CreatorBill MartinMike SchiffStarsDonal LogueMegyn PriceKevin CorriganThirty-something Irish Catholic couple Sean and Claudia deal with their three children as well as Sean's judgmental father and carefree brother.
- CreatorBryan FullerTodd HollandStarsCaroline DhavernasKatie FinneranTyron Leitso24-year-old loner B.A. Jaye lives in a trailer park and sells souvenirs in Niagara Falls. Animal figurines and dolls speak to her and force her to interact with people and try to help them.
- CreatorRand RavichStarsRobert KazinskyDilshad VadsariaAdhir KalyanA billionaire bio-engineer brings a dead police officer back to life.
- CreatorDarren StarStarsHeather LocklearAndrew ShueCourtney Thorne-SmithClassic serial drama around a group of friends living in Melrose Place, California.
- CreatorLiz HeldensStarsMark-Paul GosselaarSaniyya SidneyJamie McShaneWhen a botched U.S. government experiment turns a group of death row inmates into highly infectious vampires, an orphan girl might be the only person able to stop the ensuing crisis.