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- Aspiring film actress Penny moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.
- A thief who steals corporate secrets through the use of dream-sharing technology is given the inverse task of planting an idea into the mind of a C.E.O., but his tragic past may doom the project and his team to disaster.
- When Bella Swan moves to a small town in the Pacific Northwest, she falls in love with Edward Cullen, a mysterious classmate who reveals himself to be a 108-year-old vampire.
- Corporal Joe Bauers, a decidedly average American, is selected for a top-secret hibernation program but is forgotten and left to awaken to a future so incredibly moronic that he's easily the most intelligent person alive.
- The early years of James Logan, featuring his rivalry with his brother Victor Creed, his service in the special forces team Weapon X, and his experimentation into the metal-lined mutant Wolverine.
- Two co-dependent high school seniors are forced to deal with separation anxiety after their plan to stage a booze-soaked party goes awry.
- A story of family, religion, hatred, oil and madness, focusing on a turn-of-the-century prospector in the early days of the business.
- Common people discover that they have super powers. Their lives intertwine as a devastating event must be prevented.
- The escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, and keeping America safe.
- Through a series of freak occurrences, a group of actors shooting a big-budget war movie are forced to become the soldiers they are portraying.
- While on tour in Afghanistan, Sam's helicopter is shot down and he is presumed dead. Back home, it is his screw-up brother who looks after the family. Sam does return, but with a lot of excess baggage.
- Thirteen-year-old fledgling writer Briony Tallis irrevocably changes the course of several lives when she accuses her older sister's lover of a crime he did not commit.
- A paraplegic Marine dispatched to the moon Pandora on a unique mission becomes torn between following his orders and protecting the world he feels is his home.
- In a future where people stop aging at 25, but are engineered to live only one more year, having the means to buy your way out of the situation is a shot at immortal youth. Will Salas is accused of murder and on the run with a hostage.
- In the 1960s, superpowered humans Charles Xavier and Erik Lensherr work together to find others like them, but Erik's vengeful pursuit of an ambitious mutant who ruined his life causes a schism to divide them.
- Liz Lemon, head writer of the sketch-comedy show "TGS with Tracy Jordan", must deal with an arrogant new boss and a crazy new star while trying to run a successful television show without losing her mind.
- The brash James T. Kirk tries to live up to his father's legacy with Mr. Spock keeping him in check as a vengeful Romulan from the future creates black holes to destroy the Federation one planet at a time.
- Two aimless middle-aged losers still living at home are forced against their will to become roommates when their parents marry.
- In 1920s Los Angeles, a bedridden patient in a hospital captivates a young girl with a fantastic tale of heroes, myths, and villains on a desert island.
- As Harvard student Mark Zuckerberg creates the social networking site that would become known as Facebook, he is sued by the twins who claimed he stole their idea and by the co-founder who was later squeezed out of the business.
- A New York City writer on sex and love is finally getting married to her Mr. Big. But her three best girlfriends must console her after one of them inadvertently leads Mr. Big to jilt her.
- In 1990s Pittsburgh, a medicine peddler starts a relationship with a young woman suffering from Parkinson's disease.
- After a woman leaves a briefcase at the airport terminal, a dumb limo driver and his dumber friend set out on a hilarious cross-country road trip to Aspen to return it.
- Melinda Gordon, a newly married woman, possesses the gift of communicating with the dead. With her best friend Andrea's assistance, she helps the earthbound spirits to find peace and cross over.
- Detective Sherlock Holmes and his stalwart partner Watson engage in a battle of wits and brawn with a nemesis whose plot is a threat to all of England.