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Review
. 2013 Jun;22 Suppl 4(Suppl 4):556-66.
doi: 10.1007/s00586-012-2331-y. Epub 2012 Jun 19.

Bone and joint tuberculosis

Carlos Pigrau-Serrallach  1 , Dolores Rodríguez-Pardo
Affiliations
Review

Bone and joint tuberculosis

Carlos Pigrau-Serrallach et al. Eur Spine J. 2013 Jun.

Abstract

Introduction: Bone and joint tuberculosis has increased in the past two decades in relation with AIDS epidemics.

Material and methods: A literature review of bone and joint tuberculosis, focusing on Pott's disease.

Results: Bone and joint TB comprises a group of serious infectious diseases whose incidence has increased in the past two decades, especially in underdeveloped countries, in part due to the AIDS epidemic. Tuberculous spinal infections should be suspected in patients with an insidious, progressive history of back pain and in individuals from an endemic area, especially when the thoracic vertebrae are affected and a pattern of bone destruction with relative disc preservation and paravertebral and epidural soft tissue masses are observed. Atypical tuberculous osteoarticular manifestations involving the extraspinal skeleton, a prosthetic joint, or the trochanteric area, and nontuberculous mycobacterial infections should be considered in favorable epidemiological contexts. Surgery combined with prolonged specific antituberculous chemotherapy is mainly indicated in patients with neurological manifestations or deformities, and provides satisfactory results in most cases.

Conclusions: Spinal tuberculosis is still a relative common extra spinal manifestation of spinal tuberculosis that requires a high degree of suspicion in order to avoid neurological complications and need of surgery.

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References

    1. Andronikou S, Jadwat S, Douis H. Patterns of disease on MRI in 53 children with tuberculous spondylitis and the role of gadolinium. Pediatr Radiol. 2002;32:798–805. doi: 10.1007/s00247-002-0766-8. - DOI - PubMed
    1. Alothmqan A, ZiadM Awada A, Al-mahmood S, Al-shadoon S, Rahman M, Khan M. Tuberculous spondylitis: analysis of 69 cases from Arabia Saudi. Spine. 2001;26:E565–E570. doi: 10.1097/00007632-200112150-00020. - DOI - PubMed
    1. Babhulkar SS, Tayade WB, Babhulkar SK. Atypical spinal tuberculosis. J Bone Joint Surg (Br) 1984;66-B:239–242. - PubMed
    1. Berbari EF, Hanssen AD, Duffy MC, Steckelberg JM, Osmon DR. Prosthetic joint infection due to Mycobacterium tuberculosis: a case report and review of the literature. Am J Orthop. 1998;27:219–227. - PubMed
    1. Biviji A, Paiement G, Steinbach L. Musculoskeletal manifestations of human immunodeficiency virus infection. J Am Acad Orthop Surg. 2002;10:312–320. - PubMed

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