Dna analysis

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8.7: DNA Analysis- Blotting and Hybridization - Biology LibreTexts Ap Biology, Biochemistry Notes, Dna Analysis, Molecular Genetics, Study Biology, Biology Classroom, Biology Labs, Medical Laboratory Science, Biomedical Science

Bands of DNA in an electrophoretic gel form only if most of the DNA molecules are of the same size, such as following a PCR reaction, or restriction digestion of a plasmid. In other situations, such as after restriction digestion of chromosomal (genomic) DNA, there will be a large number of variable size fragments in the digest and it will appear as a continuous smear of DNA, rather than distinct bands.

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