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PHKG1

From Wikipedia, the free encyclopedia
PHKG1
Identifiers
AliasesPHKG1, PHKG, phosphorylase kinase catalytic subunit gamma 1
External IDsOMIM: 172470; MGI: 97579; HomoloGene: 68508; GeneCards: PHKG1; OMA:PHKG1 - orthologs
EC number2.7.11.26
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001258459
NM_001258460
NM_006213

NM_011079

RefSeq (protein)

NP_001245388
NP_001245389
NP_006204

NP_035209

Location (UCSC)Chr 7: 56.08 – 56.09 MbChr 5: 129.89 – 129.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform is an enzyme that in humans is encoded by the PHKG1 gene.[5][6]

This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164776Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025537Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wehner M, Kilimann MW (Jan 1996). "Human cDNA encoding the muscle isoform of the phosphorylase kinase gamma subunit (PHKG1)". Hum Genet. 96 (5): 616–8. doi:10.1007/bf00197422. PMID 8530014. S2CID 3257867.
  6. ^ a b "Entrez Gene: PHKG1 phosphorylase kinase, gamma 1 (muscle)".

Further reading

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