prostaglandin F receptor (Q21122493)

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mammalian protein found in Homo sapiens

PGF2 alpha receptor
prostaglandin receptor (2-alpha)
PGF receptor
prostaglandin F2-alpha receptor
PTGFR
prostanoid FP receptor
FP prostanoid receptor

Language	Label	Description	Also known as
English	prostaglandin F receptor	mammalian protein found in Homo sapiens	PGF2 alpha receptor prostaglandin receptor (2-alpha) PGF receptor prostaglandin F2-alpha receptor PTGFR prostanoid FP receptor FP prostanoid receptor

Statements

1 reference

13 November 2019

UniProt protein ID

Prostaglandin F receptor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P43088

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

prostaglandin F receptor activity

determination method

3 references

5 June 2018

Cloning and expression of a cDNA for the human prostanoid FP receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43088&geneProductId=UniProtKB:P43088

determination method

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43088&geneProductId=UniProtKB:P43088

determination method

5 June 2018

Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43088&geneProductId=UniProtKB:P43088

determination method

signal transducer activity

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43088&geneProductId=UniProtKB:P43088

determination method

prostaglandin F receptor activity

determination method

4 references

9 May 2019

Cloning and expression of a cDNA for the human prostanoid FP receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

determination method

1 reference

9 May 2019

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

extracellular region

determination method

1 reference

9 May 2019

Placenta growth factor and vascular endothelial growth factor B and C expression in microvascular endothelial cells and pericytes. Implication in autocrine and paracrine regulation of angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

plasma membrane

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

8 April 2019

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

integral component of plasma membrane

determination method

1 reference

9 May 2019

Cloning and expression of a cDNA for the human prostanoid FP receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

plasma membrane

determination method

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

biological process

G protein-coupled receptor signaling pathway

determination method

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

Cloning and expression of a cDNA for the human prostanoid FP receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

response to lipopolysaccharide

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

positive regulation of gene expression

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

response to estradiol

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

negative regulation of apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

cellular response to prostaglandin D stimulus

determination method

1 reference

9 May 2019

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

calcium-mediated signaling using intracellular calcium source

determination method

1 reference

9 May 2019

Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

determination method

1 reference

9 May 2019

Genomic structure, 5' flanking sequences, and precise localization in 1P31.1 of the human prostaglandin F receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

positive regulation of cell population proliferation

determination method

1 reference

9 May 2019

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

signal transduction

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

inflammatory response

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

adenylate cyclase-activating G protein-coupled receptor signaling pathway

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

positive regulation of cytosolic calcium ion concentration

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43088

determination method

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

prostaglandin D2

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

prostaglandin E2

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

prostaglandin F2α

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

carboprost tromethamine

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1237105

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1963683

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200799

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200963

GPCR, rhodopsin-like, 7TM

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P43088

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000359792

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000359792

ENSP00000359793

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000359793

ENSP00000359794

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000359794

ENSP00000432599

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432599

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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